Anti-IL28A antibody [A4-B9]

Anti-IL28A antibody [A4-B9]

• 概述

• 产品描述The interleukins are a broad family of well characterized cytokines, primarily of hematopoietic cell origin. As new cytokines are molecularly characterized, they are assigned an IL number to maintain a standard nomenclature. The interleukins are secreted by immune cells (mainly macrophages, B-cells or T-cells) that regulate a wide range of immune system functions. The functions of different interleukins vary from the regulation of inflammatory and immune responses to the regulation of other interleukins. Induced by viral infection and show antiviral activity, IL-28A, IL-28B and IL-29 are closely related genes that form a cytokine gene cluster on human chromosome region mapped to 19q13. IL-28A and IL-28B may play a role in antiviral immunity through up-regulation of MHC class I antigen expression and act as ligands for the heterodimeric class II cytokine receptor composed of Il-10Rβ and IL-28R.
• 产品名称Anti-IL28A antibody [A4-B9]
• 分子量22 kDa
• 种属反应性Human
• 验证应用WB,IHC-P
• 抗体类型小鼠单抗
• 免疫原Recombinant protein
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
• 亚型IgG1
• 纯化方式Protein A purified.
• 亚细胞定位Secreted
• 其它名称
  • Cytokine ZCYTO20 antibody
  • IFN-lambda-2 antibody
  • IFNL2 antibody
  more

• 应用

  WB: 1:500-1:2,000
  IHC-P: 1:50-1:200

•  

  

  Fig1: Western blot analysis of IL28A on human IL28A recombinant protein using anti- IL28A antibody at 1/1,000 dilution.

   

  

  Fig2: Western blot analysis of IL28A on HEK293 (1) and IL28A-hIgGFc transfected HEK293 (2) cell lysate using anti- IL28A antibody at 1/1,000 dilution.

   

  

  Fig3: Western blot analysis of IL28A on SK-Br-3 cell lysate using anti- IL28A antibody at 1/1,000 dilution.

   

  

  Fig4: Immunohistochemical analysis of paraffin-embedded human brain tissue using anti-IL28A antibody. Counter stained with hematoxylin.

   

  

  Fig5: Immunohistochemical analysis of paraffin-embedded human esophageal cancer tissue using anti-IL28A antibody. Counter stained with hematoxylin

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