Anti-CtIP antibody
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概述
- 产品描述The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined.
- 产品名称Anti-CtIP antibody
- 分子量100 kDa
- 种属反应性Human,Mouse
- 验证应用IHC-P,WB
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human CTIP. AA range:293-342
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称RBBP8 antibody; CTIP antibody; DNA endonuclease RBBP8 antibody; CtBP-interacting protein antibody; CtIP antibody; Retinoblastoma-binding protein 8 antibody; RBBP-8 antibody; Retinoblastoma-interacting protein and myosin-like antibody; RIM antibody; Sporulation in the absence of SPO11 protein 2 homolog antibody; SAE2 antibody;
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应用
WB: 1:500-1:2000
IHC-P: 1:100-1:300
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