Anti-TIE-1 antibody
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概述
- 产品描述The Tie-1 receptor is an endothelial specific cell surface tyrosine kinase that is indispensable for endothelial functions. Human TIE1 cDNA encodes a 1138 amino acid residue precursor protein with a putative signal peptide, an extracellular domain, and a cytoplasmic domain. Human TIE1/Fc, a disulfide linked homodimeric protein, has a calculated molecular mass of approximately 107 kDa. Tie-1 and Tie-2 are receptor tyrosine kinases (RTKs) that are exclusively expressed in endothelial cells and play important roles in endothelial cell biology.
- 产品名称Anti-TIE-1 antibody
- 分子量125kDa
- 种属反应性Human,Mouse,Rat
- 验证应用WB,ICC
- 抗体类型兔多抗
- 免疫原Synthetic peptide within human TIE-1 40-120aa.
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 25% Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Peptide affinity purified
- 亚细胞定位Cell membrane. Membrane.
- 数据链接P35590
- 其它名称JKT 14 antibody
JTK14 antibody
TIE antibody
Tie1 antibody
TIE1_HUMAN antibody
Tyrosine kinase with immunoglobulin and epidermal growth factor homology domains 1 antibody
Tyrosine Kinase with Immunoglobulin and Epidermal Growth Factor Homology Domains antibody
Tyrosine kinase with immunoglobulin-like and EGF-like domains 1 antibody
Tyrosine protein kinase receptor Tie 1 antibody
Tyrosine-protein kinase receptor Tie-1 antibody
more
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应用
WB: 1:1,000-1:5,000
ICC: 1:50-1:200
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Fig1: Western blot analysis of Tie-1 on K562 cell lysate using anti-Tie-1 antibody at 1/2,000 dilution.
Fig2: ICC staining Tie-1 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig3: ICC staining Tie-1 in SW620 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
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