Anti-ATG4C antibody [H7-E10]

Anti-ATG4C antibody [H7-E10]

• 概述

• 产品描述Atg4C (ATG4 autophagy related 4 homolog C), also known as AUTL1 (AUT-like 1, cysteine endopeptidase), AUTL3 (AUT-like 3 cysteine endopeptidase), APG4-C, autophagin-3 or cysteine protease ATG4C, is a 458 amino acid tumor suppressor protein belonging to the peptidase C54 family. Encoded by a gene that maps to human chromosome 1p31.3, Atg4C is conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish. Atg4C is highly expressed in skeletal muscle, heart, liver and testis, and localizes to cytoplasm. Functioning as a cysteine protease, which is necessary for autophagy, Atg4C cleaves the C-terminal region of either MAP1LC3, GABARAPL2 or GABARAP. Atg4C is also inhibited by N-ethylmaleimide.
• 产品名称Anti-ATG4C antibody [H7-E10]
• 分子量52 kDa
• 种属反应性Human
• 验证应用WB
• 抗体类型小鼠单抗
• 免疫原Recombinant protein
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
• 亚型IgG1
• 纯化方式Protein A purified.
• 亚细胞定位Cytoplasm
• 其它名称
  • APG4 autophagy 4 homolog C (S. cerevisiae) antibody
  • APG4 autophagy 4 homolog C antibody
  • APG4 C antibody
  more

• 应用

  WB: 1:500-1:2,000

•  

  

  Fig1: Western blot analysis of ATG4C on human ATG4C recombinant protein using anti-ATG4C antibody at 1/1,000 dilution.

   

  

  Fig2: Western blot analysis of ATG4C on HEK293 (1) and ATG4C-hIgGFc transfected HEK293 (2) cell lysate using anti-ATG4C antibody at 1/1,000 dilution.

   

  

  Fig3: Western blot analysis of ATG4C on HEK293 (1) and MOLT4 (2) cell lysate using anti-ATG4C antibody at 1/1,000 dilution.

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