Anti-Ki67 antibody
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概述
- 产品描述Ki-67 is a nuclear protein that is expressed in proliferating cells and may be required for maintaining cell proliferation. Ki-67 has been used as a marker for cell proliferation of solid tumors and some hematological malignancies. A correlation has been demonstrated between Ki-67 index and the histopathological grade of neoplasms. Assessment of Ki-67 expression in renal and ureter tumors shows a correlation between tumor proliferation and disease progression, thus making it possible to differentiate high-risk patients. Ki-67 expression may also prove to be important for distinguishing between malignant and benign peripheral nerve sheath tumors.
- 产品名称Anti-Ki67 antibody
- 分子量395/345kDa
- 种属反应性Human
- 验证应用WB, IP, IF, IHC-P
- 抗体类型兔多抗
- 免疫原Amino acids 2641-2940 mapping at the C-terminus of Ki-67 of human origin.
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃
- 存储缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified
- 亚细胞定位Nucleus, Chromosome
- 其它名称
- Antigen identified by monoclonal antibody
- Ki 67 antibody
- Antigen identified by monoclonal antibody
more
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应用
WB: 1:100-1:1,000
IP: 1-2 μg per 100-500 μg of total protein (1 ml of cell lysate)
IF: 1:50-1:500
IHC-P: 1:50-1:500
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Fig1: Western blot analysis of Ki-67 expression in MCF7 nuclear extract.
Fig2: Nuclear Ki67 in mouse mammary gland (60X microscopic magnification in oil). Dilution 1:50 in dilution buffer (0.05% BSA in PBS) Blocking: 0.1% BSA in PBS at room temp.
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
