Anti-SLC10A1 antibody
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概述
- 产品描述Sodium/bile acid cotransporter also known as the Na+-taurocholate cotransporting polypeptide (NTCP) or liver bile acid transporter (LBAT) is a protein that in humans is encoded by the SLC10A1 (solute carrier family 10 member 1) gene. Bile acid:sodium symporters participate in the enterohepatic circulation of bile acids. Two homologous transporters are involved in the reabsorption of bile acids. One of these absorbs bile acids from the intestinal lumen, the bile duct, and the kidney with an apical localization (ileal sodium/bile acid cotransporter). The other is this protein and is expressed in the basolateral membranes of hepatocytes (NTCP). As a cotransporter, NTCP binds two sodium ions and one (conjugated) bile salt molecule, thereby providing a hepatic influx of bile salts. Other transported molecules include steroid hormones, thyroid hormones and various xenobiotics.
- 产品名称Anti-SLC10A1 antibody
- 分子量38 KDa
- 种属反应性Human,Mouse,Rat,Dog,Horse,Rabbit
- 验证应用WB,ICC/IF,FC
- 抗体类型兔多抗
- 免疫原KLH conjugated synthetic peptide derived from human NTCP 21-120/349
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
- 存储缓冲液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 亚型IgG
- 纯化方式affinity purified by Protein A
- 亚细胞定位Membrane; Multi-pass membrane protein.
- 其它名称Na+/taurocholate Cotransporting Polypeptide
Na(+)/bile acid cotransporter
Cell growth-inhibiting gene 29 protein
Na / bile acid cotransporter
Na / taurocholate transport protein
Na(+)/taurocholate transport protein
NTCP
NTCP1
Sodium/taurocholate cotransporting polypeptide
Solute carrier family 10 member 1
Slc10a1 protein
Slc10a1
SBACT
SLC10A1
NTCP_HUMAN.
more
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应用
WB:1:500-2000
FC:1μg /test
IF:1:100-500
ICC/IF:1:100-500
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Fig1: Sample: K562 (human)cell Lysate at 40 ug
Primary: Anti- SLC10A1at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 38 kD
Observed band size: 48 kD
Fig2: Blank control: 293T(blue).
Primary Antibody:Rabbit Anti-SLC10A1 antibody Dilution: 1μg in 100 1μL 1X PBS containing 0.5% BSA(green);
Isotype Control Antibody: Rabbit IgG(orange) used under the same conditions );
Secondary Antibody: Goat anti-rabbit IgG-PE(white blue), Dilution: 1:200 in 1 X PBS containing 0.5% BSA.
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