Anti-APPBP1 antibody
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概述
- 产品描述Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Necessary for cell cycle progression through the S-M checkpoint. Overexpression of NAE1 causes apoptosis through deregulation of NEDD8 conjugation.
- 产品名称Anti-APPBP1 antibody
- 分子量60 KDa
- 种属反应性Human,Mouse,Rat,Dog,Pig,Horse,Rabbit
- 验证应用WB
- 抗体类型兔多抗
- 免疫原KLH conjugated synthetic peptide derived from human APPBP1 401-500/534
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
- 存储缓冲液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 亚型IgG
- 纯化方式affinity purified by Protein A
- 亚细胞定位Cell membrane. Colocalizes with APP in lipid rafts.
- 其它名称59 kDa
A 116A10.1
Amyloid beta precursor protein binding protein 1 59kD
Amyloid beta precursor protein binding protein 1 59kDa
Amyloid beta precursor protein binding protein 1
Amyloid beta precursor protein-binding protein 1
Amyloid protein binding protein 1
Amyloid protein-binding protein 1
APP BP1
APP-BP1
APPBP 1
HPP 1
HPP1
NAE 1
NAE1
NEDD8 activating enzyme E1 regulatory subunit
NEDD8 activating enzyme E1 subunit 1
NEDD8 activating enzyme E1 subunit
NEDD8-activating enzyme E1 regulatory subunit
Proto oncogene protein 1
Proto-oncogene protein 1
Protooncogene protein 1
ula 1
ULA1_HUMAN.
more
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Fig1: Sample: Placenta (Mouse) Lysate at 40 ug
Primary: Anti-APPBP1at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 60 kD
Observed band size: 60 kD
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
