Anti-CD30-L antibody
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概述
- 产品描述The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. Two transcript variants encoding different isoforms have been found for this gene.
- 产品名称Anti-CD30-L antibody
- 分子量38 kDa
- 种属反应性Human,Mouse
- 验证应用WB,IF
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human CD153. AA range:71-120
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称TNFSF8 antibody; CD30L antibody; CD30LG antibody; Tumor necrosis factor ligand superfamily member 8 antibody; CD30 ligand antibody; CD30-L antibody; CD antigen CD153 antibody;
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应用
WB: 1:500-1:2000
IF: 1:100-1:500
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
