Anti-CXCR1 antibody
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概述
- 产品描述Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity. The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.
- 产品名称Anti-CXCR1 antibody
- 分子量40 KDa
- 种属反应性Human,Mouse,Rat,Dog,Cow,Rabbit
- 验证应用WB,IHC-P
- 抗体类型兔多抗
- 免疫原KLH conjugated synthetic peptide derived from human CXCR1 186-280/350
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
- 存储缓冲液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 亚型IgG
- 纯化方式affinity purified by Protein A
- 亚细胞定位Cell membrane.
- 其它名称C C
C C CKR 1
CCCKR1
CD 181
CD128
CD181
CDw128a
Chemokine (C X C motif) receptor 1
Chemokine (C X C) receptor 1
Chemokine receptor 1
CKR 1
CMKAR1
CXCR 1
High affinity interleukin 8 receptor A
IL 8 receptor type 1
IL 8R A
IL-8RA
IL8 receptor
IL8 receptor type 1
IL8R1
IL8RA
IL8RBA
Interleukin 8 receptor alpha
Interleukin 8 receptor type 1. Interleukin 8 receptor type A
CXCR1_HUMAN
C-C
CD181
CKR-1
IL8R1
CDw128a
C-C-CKR-1.
more
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应用
WB:1:500-2000
IHC-P:1:400-800
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Fig1: Sample:
HepG2(Human) Cell Lysate at 40 ug
Primary: Anti- CXCR1 at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 40 kD
Observed band size: 40 kD
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
