Anti-ACP5 antibody [A11-E6]

Anti-ACP5 antibody [A11-E6]

• 概述

• 产品描述Tartrate-resistant acid phosphatase (TRAP, ACP5) is an iron containing glycoprotein that catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. TRAP is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate. TRAP is a relatively minor lysosomal enzyme which may be activated in certain pathologies such as Hodgkin's disease and B- and T-cell leukemias. Receptor activator of NFkB ligand (RANKL) plays an essential role in osteoclast differentiation and activation by increasing the expression of protease osteoclast markers such as TRAP. TRAP has collagenolytic activity and plays a major role in ligament degradation.

• 产品名称Anti-ACP5 antibody [A11-E6]

• 分子量37 kDa

• 种属反应性Human

• 验证应用WB,IHC-P

• 抗体类型小鼠单抗

• 免疫原Recombinant protein

• 偶联Non-conjugated

• 性能

• 形态Liquid

• 浓度2 mg/mL.

• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.

• 存储缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

• 亚型IgG1

• 纯化方式Protein A purified.

• 亚细胞定位Lysosome.

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• ​其它名称

  more

  • Type 5 acid phosphatase antibody

  • Acid phosphatase 5 tartrate resistant antibody

  • Acid phosphatase 5, tartrate resistant antibody

• 应用

  WB: 1:500-1:1,000
  IHC-P: 1:50-1:200

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  Fig1: Western blot analysis of ACP5 on human ACP5 recombinant protein using anti-ACP5 antibody at 1/1,000 dilution.

   

  

  Fig2: Western blot analysis of ACP5 on HEK293 (1) and ACP5-hIgGFc transfected HEK293 (2) cell lysate using anti-ACP5 antibody at 1/1,000 dilution.

   

  

  Fig3: Western blot analysis of ACP5 on different cell lysate using anti-ACP5 antibody at 1/1,000 dilution.
  Positive control: Line1: A431 Line2: T47D Line3: HepG2 Line4: MOLT4 Line5: Jurkat Line6: Hela

   

  

  Fig4: Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-ACP5 antibody. Counter stained with hematoxylin.

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