Anti-CD7 antibody [F8-D4]

Anti-CD7 antibody [F8-D4]

• 概述

• 产品描述CD7 (also designated T cell leukemia antigen) is a type I transmembrane glycoprotein that is expressed on pluripotential hemapoietic cells, most human thymocytes and some peripheral blood T cells. CD7 is a marker for pluripotential stem cell leukemias and T cell acute lymphocytic leukemia. A role for CD7 in the activation of T cells with g/d receptors has been suggested. CD8 T cells from patients infected with HIV-1 displayed profound down-modulation of CD7 expression as compared with healthy subjects. CD7 is among the pan-T-cell antigens down-regulated in acute infectious mononucleosis.

• 产品名称Anti-CD7 antibody [F8-D4]

• 分子量25 kDa

• 种属反应性Human

• 验证应用WB,IHC-P,FC

• 抗体类型小鼠单抗

• 免疫原Recombinant protein

• 偶联Non-conjugated

• 性能

• 形态Liquid

• 浓度2 mg/mL.

• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.

• 存储缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

• 亚型IgG1

• 纯化方式Protein A purified.

• 亚细胞定位Membrane.

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• ​其它名称

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  • CD7 antibody

  • CD7 antigen (p41) antibody

  • CD7 antigen antibody

• 应用

  WB: 1:500-1:1,000
  IHC-P: 1:50-1:200
  FC: 1:100-1:200

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  Fig1: Western blot analysis of CD7 on human CD7 recombinant protein using anti-CD7 antibody at 1/1,000 dilution.

   

  

  Fig2: Western blot analysis of CD7 on HEK293 (1) and CD7-hIgGFc transfected HEK293 (2) cell lysate using anti-CD7 antibody at 1/1,000 dilution.

   

  

  Fig3: Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using anti-CD7 antibody. Counter stained with hematoxylin.

   

  

  Fig4: Flow cytometric analysis of Jurkat cells with CD7 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).

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