Anti-TRAFD1 antibody [E7-E6]
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概述
- 产品描述Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. May negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3.
- 产品名称Anti-TRAFD1 antibody [E7-E6]
- 分子量65 kDa
- 种属反应性Human
- 验证应用WB,ICC,FC
- 抗体类型小鼠单抗
- 免疫原Recombinant protein
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度2 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG1
- 纯化方式Protein A purified.
- 亚细胞定位--
- 其它名称
- FLN29 antibody
- FLN29 gene product antibody
- Protein FLN29 antibody
more
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应用
WB: 1:500-1:1,000
ICC: 1:50-1:200
FC: 1:100-1:200
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Fig1: Western blot analysis of TRAFD1 on human TRAFD1 recombinant protein using anti-TRAFD1 antibody at 1/1,000 dilution.
Fig2: Western blot analysis of TRAFD1 on HEK293 (1) and TRAFD1-hIgGFc transfected HEK293 (2) cell lysate using anti-TRAFD1 antibody at 1/1,000 dilution.
Fig3: Western blot analysis of TRAFD1 on different cell lysate using anti-TRAFD1 antibody at 1/1,000 dilution.
Positive control:
Line1:HEK293 Line2:Raji Line3:Jurkat
Fig4: ICC staining TRAFD1 (green) in HepG2 cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig5: Flow cytometric analysis of Hela cells with TRAFD1 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; purple).
特别提示:本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!