Anti-SMAD6 antibody [H6-H3]

Anti-SMAD6 antibody [H6-H3]

• 概述

• 产品描述Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad) have been implicated as downstream effectors of TGFβ/BMP signaling. Smad1 (also designated Madr1 or JV4-1), Smad5 and mammalian Smad8 (also designated Smad9 or MADH6) are effectors of BMP2 and BMP4 function while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGFβ and activin-mediated growth modulation (2-5,8). Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGFβ signaling by interfering with TGFβ-mediated phosphorylation of other Smad family members.
• 产品名称Anti-SMAD6 antibody [H6-H3]
• 分子量53 kDa
• 种属反应性Human
• 验证应用WB
• 抗体类型小鼠单抗
• 免疫原Recombinant protein
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
• 亚型IgG1
• 纯化方式Protein A purified.
• 亚细胞定位Nucleus.
• 其它名称
  • hSMAD6 antibody
  • MAD homolog 6 antibody
  • MADH6 antibody
  more

• 应用

  WB: 1:500-1:1,000

•  

  

  Fig1: Western blot analysis of SMAD6 on different cell lysates using anti-SMAD6 antibody at 1/1,000 dilution.
  Positive control:
  Lane 1: A431
  Lane 2: A431
  Lane 3: Hela
  Lane 4: Jurkat

特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！