Anti-SLINGSHOT-1L antibody [G9-C11]

Anti-SLINGSHOT-1L antibody [G9-C11]

• 概述

• 产品描述Slingshot homolog (SSH) family of phosphatases, which regulate actin filament dynamics. The SSH proteins dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Cofilin is inactivated by kinases such as LIM domain kinase-1 (LIMK1), which may also be dephosphorylated and inactivated by SSH proteins. The SSH family thus appears to play a role in actin dynamics by reactivating cofilin proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
• 产品名称Anti-SLINGSHOT-1L antibody [G9-C11]
• 分子量116 kDa
• 种属反应性Human
• 验证应用IHC-P,FC
• 抗体类型小鼠单抗
• 免疫原Recombinant protein
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
• 亚型IgG1
• 纯化方式Protein A purified.
• 亚细胞定位Cytoplasm
• 其它名称
  • AW551225 antibody
  • Coro1c antibody
  • coronin, actin binding protein 1C antibody
  more

• 应用

  IHC-P: 1:50-1:200
  FC: 1:50-1:100

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  Fig1: Immunohistochemical analysis of paraffin-embedded human ovarian cancer tissue using anti- Slingshot homolog 1 antibody. Counter stained with hematoxylin.

   

  

  Fig2: Flow cytometric analysis of Hela cells with Slingshot homolog 1 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).

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