Anti-BAI1 antibody
-
概述
- 产品描述Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 contains at least one 'functional' p53-binding site within an intron, and its expression has been shown to be induced by wildtype p53. There are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3 which along with BAI1 have similar tissue specificities and structures, however only BAI1 is transcriptionally regulated by p53. BAI1 is postulated to be a member of the secretin receptor family,
- 产品名称Anti-BAI1 antibody
- 分子量130-170 kDa
- 种属反应性Human, Rat, Mouse
- 验证应用WB, IHC-P
- 抗体类型兔多抗
- 免疫原Synthetic Peptide of BAI1
- 偶联Non-conjugated
-
性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称Brain-specific angiogenesis inhibitor 1 antibody;
-
应用
WB: 1:500-1:2000
IHC-P: 1:100-1:300
-
Fig1: Western blot analysis of 1) 293T, 2)Mouse Brain Tissue, 3) Rat Brain Tissue with BAI1 Rabbit pAb diluted at 1:2,000.
Fig2: Immunohistochemical analysis of paraffin-embedded Rat Brain Tissue using BAI1 Rabbit pAb diluted at 1:200.
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
