Anti-SSTR3 antibody [5H-8E]

Anti-SSTR3 antibody [5H-8E]

• 概述

• 产品描述There are five somatostatin receptor subtypes termed SSTR 1 to 5. They are G protein coupled receptors characterized by seven transmembrane helices with an extracellular amino terminal domain and an intracellular carboxy terminus. These receptors are activated by somatostatin secreted by nerve and endocrine cells and function in the regulation of numerous physiological processes such as the secretion of insulin, glucagon and growth hormone. The SSTRs also play a role in cell growth induced by neuronal excitation in both the central and peripheral nervous system. Somatostatin receptors have been implicated in numerous diseases ranging from Alzheimer's to cancers of the gastrointestinal tract, breast, prostate, and pituitary. Somatostatin receptor type 3 (SSTR3) is a Somatostatin Receptor. Unlike SSTR1 and SSTR2, SSTR3 is functionally coupled to adenylyl cyclase. Expression of SSTR3 has been reported in brain, breast, eye, gastrointestinal tract, pancreas, and thyroid.
• 产品名称Anti-SSTR3 antibody [5H-8E]
• 分子量46 kDa
• 种属反应性Human
• 验证应用WB,FC
• 抗体类型小鼠单抗
• 免疫原Recombinant protein
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
• 亚型IgG1
• 纯化方式Protein A purified.
• 亚细胞定位Cell membrane.
• 其它名称
  • OTTHUMP00000028737 antibody
  • Smstr 3 antibody
  • Smstr3 antibody
  more

• 应用

  WB: 1:500-1:2,000
  FC: 1:50-1:100

•  

  

  Fig1: Western blot analysis of SSTR3 on human SSTR3 recombinant protein using anti-SSTR3 antibody at 1/1,000 dilution.

   

  

  Fig2: Western blot analysis of SSTR3 on HEK293 (1) and SSTR3-hIgGFc transfected HEK293 (2) cell lysate using anti-SSTR3 antibody at 1/1,000

   

  

  Fig3: Western blot analysis of SSTR3 on different cell lysate using anti-SSTR3 antibody at 1/1,000 dilution.
  Positive control: Line1: Hela Line2: PANC-1 Line3: PC-12 Line4: SK-N-SH Line5: U937 Line6: HepG2

   

  

  Fig4: Flow cytometric analysis of Hela cells with SSTR3 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).

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