Anti-SERPINE1 antibody [H9-D5]

Anti-SERPINE1 antibody [H9-D5] 

• 概述

• 产品描述SERPINE1 is a protein of the serpin serine proteinase inhibitor family. It has shown to regulate uPA (urokinase-type plasminogen activator) and tPA (tissue plasminogen activator), resulting in the inhibition of proteolytic activity. Members of the serpin family generally complex with their target proteinases, then disassociate slowly into cleaved species that fold into stable inactive forms. uPA is a serine proteinase that is a member of the Trypsin family. It is responsible for the cleavage of plasminogen at the Arg-Val bond to produce plasmin. uPA consists of two chains designated A and B. The A chain can be cleaved, resulting in low and high molecular mass forms of uPA.
• 产品名称Anti-SERPINE1 antibody [H9-D5]
• 分子量45 kDa
• 种属反应性Human,Mouse
• 验证应用WB,IHC-P,FC
• 抗体类型小鼠单抗
• 免疫原Recombinant protein
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
• 亚型IgG1
• 纯化方式Protein A purified.
• 亚细胞定位Secreted.
• 其它名称
  • Clade E antibody
  • Endothelial plasminogen activator inhibitor antibody
  • Nexin antibody
  more

• 应用

  WB: 1:500-1:1,000
  IHC-P: 1:100-1:500
  FC: 1:100-1:200

•  

  

  Fig1: Western blot analysis of SERPINE1 on human SERPINE1 recombinant protein using anti-SERPINE1 antibody at 1/1,000 dilution.

   

  

  Fig2: Western blot analysis of SERPINE1 on HEK293 (1) and SERPINE1-hIgGFc transfected HEK293 (2) cell lysate using anti-SERPINE1 antibody at 1/1,000 dilution.

   

  

  Fig3: Immunohistochemical analysis of paraffin-embedded lung cancer tissue using anti-SERPINE1 antibody. Counter stained with hematoxylin.

   

  

  Fig4: Immunohistochemical analysis of paraffin-embedded kidney cancer tissues using anti-SERPINE1 antibody. Counter stained with hematoxylin.

   

  

  Fig5: Flow cytometric analysis of NIH/3T3 cells with SERPINE1 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).

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