Anti-TGFb1 antibody [B2-F6]

Anti-TGFb1 antibody [B2-F6]

• 概述

• 产品描述The transforming growth factors b (TGFβ) superfamily is composed of numerous growth and differentiation factors, including TGFβ1-3. TGFβs are secreted from cells as latent complexes consisting of mature dimeric growth factor, the latency-associated propeptide (LAP) and a distinct gene product, latent TGFβ binding protein LTBP. Members of the TGF superfamily are involved in embryonic development and adult tissue homeostasis. The precursor of TGFβ is cleaved into mature TGFβ and LAP (latency associated peptide). Mature TGFβ remains associated with LAP by non-covalent interactions that block TGFβ from binding to its receptor.
• 产品名称Anti-TGFb1 antibody [B2-F6]
• 分子量44 kDa
• 种属反应性Human
• 验证应用WB,IHC-P,FC
• 抗体类型小鼠单抗
• 免疫原Recombinant protein
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
• 亚型IgG1
• 纯化方式Protein A purified.
• 亚细胞定位Secreted. Extracellular matrix.

• 应用

  WB: 1:500-1:1,000
  IHC-P: 1:100-1:500
  FC: 1:100-1:200

•  

  

  Fig1: Western blot analysis of TGF beta 1 on human TGF beta 1 recombinant protein using anti- TGF beta 1 antibody at 1/1,000 dilution.

   

  

  Fig2: Immunohistochemical analysis of paraffin-embedded human lung tissue using anti- TGF beta 1 antibody. Counter stained with hematoxylin.

   

  

  Fig3: Immunohistochemical analysis of paraffin-embedded human lymphoid tissue using anti- TGF beta 1 antibody. Counter stained with hematoxylin.

   

  

  Fig4: Flow cytometric analysis of A549 cells with TGF beta 1 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).

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