Anti-Annexin A3 antibody
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概述
- 产品描述The annexin family of calcium-binding proteins is composed of at least ten mammalian genes and is characterized by a conserved core domain, which binds phospholipids in a Ca2+-dependent manner, and a unique amino-terminal region, which may confer binding specificity. Annexin family members have been implicated as regulators of such diverse processes as ion flux, endocytosis, exocytosis and cellular adhesion. Annexin III, also known as ANXA3, Annexin A3, Lipocortin III, PAP-III (placental anticoagulant protein III), 35-α calcimedin or ANX3, belongs to the annexin family and contains four Annexin repeats. Annexin III exhibits a variety of functions, including anti-coagulent properties, an inhibitory role towards phospholipase A2 (PLA2) and an enzymatic function, cleaving the cyclic bond of inositol 1,2-cyclic phosphate to produce inositol 1-phosphate.
- 产品名称Anti-Annexin A3 antibody
- 分子量36 kDa
- 种属反应性Human,Mouse,Rat
- 验证应用WB,IHC-P,FC
- 抗体类型兔多抗
- 免疫原Recombinant protein with Human Annexin A3 aa 1-350.
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Protein affinity purified.
- 亚细胞定位Cytoplasm. Secreted. Plasma Membrane.
- 其它名称2-cyclic phosphate 2-phosphohydrolase antibody
35-alpha calcimedin antibody
Annexin A3 antibody
Annexin III antibody
Annexin-3 antibody
ANX3 antibody
ANXA 3 antibody
Anxa3 antibody
ANXA3_HUMAN antibody
Calcimedin 35 alpha antibody
Inositol 1 2 cyclic phosphate 2 phosphohydrolase antibody
Inositol 1 antibody
Lipocortin III antibody
OTTHUMP00000160701 antibody
OTTHUMP00000219237 antibody
OTTHUMP00000219238 antibody
PAP III antibody
PAP-III antibody
Placental anticoagulant protein III antibody
more
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应用
WB: 1:500-1:2,000
IHC-P: 1:50-1:200
FC: 1:50-1:100
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Fig1: Western blot analysis of Annexin A3 on different lysates using anti-Annexin A3 antibody at 1/1,000 dilution.
Positive control:
Lane 1: Siha
Lane 2: Hela
Lane 3: Rat spleen tissue
Lane 4: Rat liver tissue
Lane 5: Mouse lung tissue
Fig2: Immunohistochemical analysis of paraffin-embedded rat kidney tissue using anti-Annexin A3 antibody. Counter stained with hematoxylin.
Fig3: Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-Annexin A3 antibody. Counter stained with hematoxylin.
Fig4: Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-Annexin A3 antibody. Counter stained with hematoxylin.
Fig5: Immunohistochemical analysis of paraffin-embedded human prostate tissue using anti-Annexin A3 antibody. Counter stained with hematoxylin.
Fig6: Flow cytometric analysis of A431 cells with Annexin A3 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.
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