Anti-Collagen II antibody
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概述
- 产品描述This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene.
- 产品名称Anti-Collagen II antibody
- 分子量117 KDa
- 种属反应性Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Rabbit,Guinea Pig
- 验证应用WB,IHC-P,ICC/IF
- 抗体类型兔多抗
- 免疫原KLH conjugated synthetic peptide derived from human Collagen II 1201-1300/1487
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
- 存储缓冲液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 亚型IgG
- 纯化方式affinity purified by Protein A
- 亚细胞定位Secreted, extracellular space, extracellular matrix.
- 其它名称Collagen II alpha 1
COL2A1
COL2A1 protein
collagen, type II, alpha 1
collagen alpha-1(II)
type II collagen
alpha-1 type II collagen
alpha1 type II collagen
Col2a1
AOM
Cartilage collagen
Chondrocalcin
COL11A3
Collagen alpha 1(II) chain precursor
Collagen II alpha 1 polypeptide
Collagen type II alpha 1 (primary osteoarthritis spondyloepiphyseal dysplasia congenital)
MGC131516
SEDC
Collagen alpha-1(II) chain
Alpha-1 type II collagen
CO2A1_HUMAN.
more
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应用
WB:1:500-2000
IHC-P:1:400-800
IF:1:100-500
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Fig1: Sample:
293T (human)Cell Lysate at 40 ug
A549 (human)Cell Lysate at 40 ug
MCF-7 (human)Cell Lysate at 40 ug
HepG2 (human)Cell Lysate at 40 ug
Placenta (mouse) Lysate at 40 ug
MG63 (human)Cell Lysate at 40 ug
Primary: Anti- Collagen II at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 117 kD
Observed band size: 120 kD
特别提示:本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!