Anti-CHRNA2 antibody [H9-G12]

Anti-CHRNA2 antibody [H9-G12] 

• 概述

• 产品描述After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Defects in CHRNA2 are the cause of nocturnal frontal lobe epilepsy type 4 (ENFL4). ENFL4 is an autosomal dominant epilepsy characterized by nocturnal seizures associated with fear sensation, tongue movements, and nocturnal wandering, closely resembling nightmares and sleep walking.
• 产品名称Anti-CHRNA2 antibody [H9-G12]
• 分子量60 kDa
• 种属反应性Human,Rat
• 验证应用WB
• 抗体类型小鼠单抗
• 免疫原Recombinant protein
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
• 纯化方式Protein A purified.
• 亚细胞定位Cell junction, Cell membrane
• 其它名称
  • ACHA2_HUMAN antibody
  • AChR antibody
  • Cholinergic receptor nicotinic alpha 2 antibody
  more

• 应用

  WB: 1:500-1:2,000

•  

  

  Fig1: Western blot analysis of CHRNA2 on human CHRNA2 recombinant protein using anti-CHRNA2 antibody at 1/1,000 dilution.

   

  

  Fig2: Western blot analysis of CHRNA2 on HEK293 (1) and CHRNA2-hIgGFc transfected HEK293 (2) cell lysate using anti-CHRNA2 antibody at 1/1,000 dilution.

   

  

  Fig3: Western blot analysis of CHRNA2 on different cell lysate using anti-CHRNA2 antibody at 1/1,000 dilution.
  Positive control:
  Line1: SK-N-SH
  Line2: SH-SY5Y
  Line3: Membrane protein lysate of C6
  Line4: SW480

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