Anti-Pan Cadherin antibody
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概述
- 产品描述The cadherins are a large family of cell adhesion molecules involved in calcium-dependent recognition and adhesion events (1). Synaptic remodeling has been postulated as a mechanism underlying synaptic plasticity, and cadherin adhesion molecules are thought to be a regulator of such a process. Findings suggest that cadherin regulates dendritic spine morphogenesis and related synaptic functions, presumably cooperating with cadherin-independent adhesive mechanisms to maintain spine-axon contacts (2). Human retinoblastoma and normal retinal tissue the type of cadherin, its relationship with cytoplasmic catenins, and its participation in invasion has been examined. Retinoblastoma cells, in contrast with normal retina, express an cadherin-2/catenin complex that is irregularly distributed and weakly linked to the cytoskeleton. In retinoblastoma, this complex acts as an invasion promoter (3).
- 产品名称Anti-Pan Cadherin antibody
- 分子量140kDa
- 种属反应性Human,Mouse,Rat
- 验证应用WB,ICC,IHC-P,FC,IP
- 抗体类型兔多抗
- 免疫原peptide
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at -20 ℃. Stable for 12 months from date of receipt
- 存储缓冲液1*TBS (pH7.4), 0.5%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Tissue culture supernatant
- 亚细胞定位Cytoplasm, Cell junction
- 其它名称
- Cadherin antibody
- CDH3 antibody
- CDHP antibody
more
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应用
WB: 1:1,000
ICC: 1:100
IHC-P: 1:100
IP: 1:40
FC: 1:30
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Fig1: Western blot analysis on C6 cell lysate using anti-Pan-Cadherin.
Fig2: Immunohistochemical staining of paraffin-embedded human cervical carcinoma tissue using anti-Pan-Cadherin.
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
