Anti-Figla antibody
-
概述
- 产品描述Ovarian folliculogenesis is an intricate process involving interactions between germ and somatic cells in mammalians. FIGLA (folliculogenesis specific basic helix-loop-helix), also known as POF6, BHLHC8 or FIGALPHA, is a 219 amino acid nuclear protein expressed in fetal ovary and germ cells. FIGLA contains one basic helix-loop-helix (bHLH) domain and heterodimerizes with E12, a transcription factor that influences gene expression during B cell maturation. Acting as a germline specific transcription factor and a key player of ovarian folliculogenesis, FIGLA regulates the expression of multiple oocyte-specific genes that are required for fertilization and early embryonic survival. Mutations in the gene encoding FIGLA may be the cause of Premature Ovarian Failure (POF), a genetically heterogenous disorder that leads to hypergonadotropic ovarian failure and infertility. POF is characterized by amenorrhea, hypoestrogenism and elevated serum gonadotropin concentrations. FIGLA inhibits the expression of male germ cell specific genes during oogenesis.
- 产品名称Anti-Figla antibody
- 种属反应性Mouse
- 验证应用ICC
- 抗体类型兔多抗
- 免疫原peptide
- 偶联Non-conjugated
-
性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Peptide affinity purified
- 亚细胞定位Cytoplasm
- 其它名称
- bHLHc8 antibody
- Class C basic helix-loop-helix protein 8 antibody
- Factor in the germline alpha antibody
more
-
-
Fig1: Immunocytochemical staining of mouse three-cell embryosusing anti-Figla rabbit polyclonal antibody(red). (Green: F-actin, Blue: DAPI)
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
