Anti-p53RFP antibody
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概述
- 产品描述caution:Lacks the His residue in the RING-type domain 2 that is one of the conserved features of the family. domain:The RING-type zinc finger domain mediates binding to an E2 ubiquitin-conjugating enzyme. E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a TP53/p53-dependent but caspase-independent mechanism. pathway:Protein modification; protein ubiquitination. PTM:Auto-ubiquitinated. Belongs to the RBR family. RNF144 subfamily. Contains 1 IBR-type zinc finger. Contains 2 RING-type zinc fingers. subunit:Interacts with UBE2L3, UBE2L6 and LCMT2. tissue specificity:Broadly expressed, with lowest levels in brain, spleen and thymus.
- 产品名称Anti-p53RFP antibody
- 分子量35 kDa
- 种属反应性Human, Mouse
- 验证应用WB
- 抗体类型兔多抗
- 免疫原Synthesized peptide derived from the Internal region of human p53RFP.
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称
- RNF144B antibody; IBRDC2 antibody; P53RFP antibody; E3 ubiquitin-protein ligase RNF144B antibody; IBR domain-containing protein 2 antibody; RING finger protein 144B antibody; p53-inducible RING finger protein antibody;
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Fig1: Western Blot analysis of various cells using p53RFP Polyclonal Antibody
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
