Anti-P63 antibody
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概述
- 产品描述Tumor protein p63 is a member of the p53 family of transcription factors. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. TP63 mutations underlie several malformation syndromes that include cleft lip and/or palate as a hallmark feature. p63 immunostaining has utility for head and neck squamous cell carcinomas, differentiating prostatic adenocarcinoma (the most common type of prostate cancer) and benign prostatic tissue; normal prostatic glands stain with p63 (as they have basal cells), while the malignant glands in prostatic adenocarcinoma (which lacks these cells) do not. P63 is also helpful in distinguishing poorly differentiated squamous cell carcinoma from small cell carcinoma or adenocarcinoma.
- 产品名称买二赠二Anti-P63 antibody
- 分子量77 kDa
- 种属反应性Human,Mouse,Rat
- 验证应用WB,IHC-P
- 抗体类型兔多抗
- 免疫原peptide
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Peptide affinity purified
- 亚细胞定位Nucleus
- 其它名称
- AIS antibody
- Amplified in squamous cell carcinoma antibody
- B(p51A) antibody
more
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应用
WB: 1:500-1:1,000
IHC-P: 1:100-1:200
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Fig1: Western blot analysis on Hela and MCF-7 cell lysates using anti-p63 rabbit polyclonal antibodies.
Fig2: Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using anti- p63 rabbit polyclonal antibody.
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
