Anti-IL-17Rα antibody
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概述
- 产品描述Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms.
- 产品名称Anti-IL-17Rα antibody
- 分子量90 kDa
- 种属反应性Human
- 验证应用IHC-P, WB
- 抗体类型兔多抗
- 免疫原Synthesized peptide derived from human IL-17Rα
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 亚细胞定位Cell membrane, Secreted.
- 其它名称
- Interleukin-17 receptor A antibody
- IL-17 receptor A antibody
- IL-17RA antibody
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应用
IHC-P: 1:50-200
WB: 1:500-1:2000
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
