Anti-p57 antibody
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概述
- 产品描述This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.
- 产品名称Anti-p57 antibody
- 分子量32 kDa
- 种属反应性Human, Mouse, Rat
- 验证应用WB, IHC-P
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human p57Kip2 around the non-acetylation site of Lys278. AA range:241-290
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称
- CDKN1C antibody; KIP2 antibody; Cyclin-dependent kinase inhibitor 1C antibody; Cyclin-dependent kinase inhibitor p57 antibody; p57Kip2 antibody;
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应用
WB: 1:500-1:2000
IHC-P: 1:100-1:300
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Fig1: Western Blot analysis of Jurkat cells using p57 Polyclonal Antibody.. Secondary antibody(catalog#:HA1001) was diluted at 1:20000
Fig2: Immunohistochemical analysis of paraffin-embedded human-mammary-cancer, antibody was diluted at 1:100
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