Anti-ATP2A1 antibody

Anti-ATP2A1 antibody

• 概述

• 产品描述Key regulator of striated muscle performance by acting as the major Ca2+ ATPase responsible for the reuptake of cytosolic Ca2+ into the sarcoplasmic reticulum. Catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction.

• 产品名称Anti-ATP2A1 antibody

• 分子量110 kDa

• 种属反应性Human,Mouse,Rat

• 验证应用WB,IHC-P,FC

• 抗体类型兔多抗

• 免疫原Synthetis peptide within rat ATP2A1 aa 20-50.

• 偶联Non-conjugated

• 性能

• 形态Liquid

• 浓度1 mg/mL.

• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.

• 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

• 亚型IgG

• 纯化方式Peptide affinity purified.

• 亚细胞定位Endoplasmic reticulum membrane. Sarcoplasmic reticulum membrane.

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• 其它名称fast twitch skeletal muscle isoform antibody
  AT2A1_HUMAN antibody
  ATP2A antibody
  ATP2A1 antibody
  ATPase Ca++ transporting cardiac muscle fast twitch 1 antibody
  ATPase Ca++ transporting fast twitch 1 antibody
  ATPase, Ca(2+)-transporting fast twitch 1 antibody
  Calcium pump 1 antibody
  Calcium transporting ATPase sarcoplasmic reticulum type fast twitch skeletal muscle isoform antibody
  Calcium-transporting ATPase sarcoplasmic reticulum type antibody
  EC 3.6.3.8 antibody
  Endoplasmic reticulum class 1/2 Ca(2+) ATPase antibody
  Fast skeletal muscle SR calcium ATPase antibody
  OTTHUMP00000162561 antibody
  OTTHUMP00000162562 antibody
  Sarcoendoplasmic reticulum calcium ATPase antibody
  Sarcoplasmic reticulum Ca(2+)-ATPase 1 antibody
  Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 antibody
  SERCA 1 antibody
  SERCA1 antibody
  SERCA1 truncated isoform, included antibody
  SR Ca(2+) ATPase 1 antibody
  SR Ca(2+)-ATPase 1 antibody

  more

• 应用

  WB: 1:500-1:1,000
  IHC-P: 1:50-1:200
  FC: 1:50-1:100

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  Fig1: Western blot analysis of ATP2A1 on different lysates using anti-ATP2A1 antibody at 1/500 dilution.
  Positive control:
  Lane 1: Mouse skeletal muscle tissue
  Lane 2: Human skeletal muscle tissue

   

  

  Fig2: Immunohistochemical analysis of paraffin-embedded rat skeletal muscle tissue using anti-ATP2A1 antibody. Counter stained with hematoxylin.

   

  

  Fig3: Immunohistochemical analysis of paraffin-embedded human fetal skeletal muscle tissue using anti-ATP2A1 antibody. Counter stained with hematoxylin.

   

  

  Fig4: Immunohistochemical analysis of paraffin-embedded mouse skeletal muscle tissue using anti-ATP2A1 antibody. Counter stained with hematoxylin.

   

  

  Fig5: Flow cytometric analysis of 293T cells with ATP2A1 antibody at 1/100 dilution (fuchsia) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.

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特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！