Anti-FGFR-4 antibody
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概述
- 产品描述The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. The genomic organization of this gene, compared to members 1-3, encompasses 18 exons rather than 19 or 20. Although alternative splicing has been observed, there is no evidence that the C-terminal half of the IgII
- 产品名称Anti-FGFR-4 antibody
- 分子量85 kDa
- 种属反应性Human
- 验证应用WB
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from the Internal region of human FGFR4. AA range:91-140
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称
- FGFR4 antibody; JTK2 antibody; TKF antibody; Fibroblast growth factor receptor 4 antibody; FGFR-4 antibody; CD334 antibody;
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Fig1: Western blot analysis of 293T 3T3 lysis using FGFR4 antibody. Antibody was diluted at 1:500. Secondary antibody（catalog#：HA1001) was diluted at 1:20000
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