Anti-CYP2C19 antibody

Anti-CYP2C19 antibody

• 概述

• 产品描述Responsible for the metabolism of a number of therapeutic agents such as the anticonvulsant drug S-mephenytoin, omeprazole, proguanil, certain barbiturates, diazepam, propranolol,
• 产品名称Anti-CYP2C19 antibody
• 分子量56 KDa
• 种属反应性Human
• 验证应用WB,IHC-P
• 抗体类型兔多抗
• 免疫原KLH conjugated synthetic peptide derived from human CYP2C19 201-300/490
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度1 mg/mL.
• 存放说明Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
• 存储缓冲液Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
• 亚型IgG
• 纯化方式affinity purified by Protein A
• 亚细胞定位Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
• 其它名称AI266900
  CYP2C
  CYP2C19
  CYP2C37
  CYP2C50
  Cyp2c54
  CYP450-2C
  CPCJ
  CYPIIC17
  CYPIIC19
  EG404195
  LOC293989
  MGC109053
  P450-11A
  P450C2C
  P450IIC19
  CP2CJ_HUMAN Cytochrome P450 2C19
  R)-limonene 6-monooxygenase
  (S)-limonene 6-monooxygenase
  (S)-limonene 7-monooxygenase
  CYPIIC17
  CYPIIC19
  Cytochrome P450-11A
  Cytochrome P450-254C
  Mephenytoin 4-hydroxylase.
  more

• 应用

  WB:1:500-2000
  IHC-P:1:400-800

•  

  

  Fig1: Paraformaldehyde-fixed, paraffin embedded (Human liver cancer); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37℃ for 30min; Antibody incubation with (CYP2C19) Polyclonal Antibody, Unconjugatedat 1:400 overnight at 4℃, followed by operating according to SP Kit(Rabbit) (sp-0023) instructions and DAB staining.

   

  

  Fig2: Sample:
  HepG2(Human) Cell Lysate at 30 ug
  A549(Human) Cell Lysate at 30 ug
  Primary: Anti- CYP2C19 at 1/300 dilution
  Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
  Predicted band size: 56 kD
  Observed band size: 56 kD

特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！