Anti-RO60 antibody
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概述
- 产品描述disease:Sera from patients with systemic lupus erythematosus (SLE) often contain antibodies that react with the normal cellular SSA2 protein as if this antigen was foreign. RNA-binding protein that binds to several small cytoplasmic RNA molecules known as Y RNAs. May stabilize these RNAs from degradation. PTM:Phosphorylated upon DNA damage, probably by ATM or ATR. Belongs to the Ro 60 kDa family. Contains 1 TROVE domain. subunit:Found in a complex with PUF60 and Y5 RNA. Interacts with RIP11.
- 产品名称Anti-RO60 antibody
- 分子量70 kDa
- 种属反应性Human
- 验证应用WB
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human TROVE2. AA range:311-360
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称
- TROVE2 antibody; RO60 antibody; SSA2 antibody; 60 kDa SS-A/Ro ribonucleoprotein antibody; 60 kDa Ro protein antibody; 60 kDa ribonucleoprotein Ro antibody; RoRNP antibody; Ro 60 kDa autoantigen antibody; Sjoegren syndrome antigen A2 antibody; Sjoegren syndrome type A antigen antibody; SS-A antibody; TROVE domain family member 2 antibody;
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