Anti-Siah-1/2 antibody
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概述
- 产品描述This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.
- 产品名称Anti-Siah-1/2 antibody
- 分子量34 kDa
- 种属反应性Human, Mouse, Rat
- 验证应用WB, IHC-P, IF
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human SIAH1. AA range:181-230
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称
- SIAH1 antibody; HUMSIAH antibody; E3 ubiquitin-protein ligase SIAH1 antibody; Seven in absentia homolog 1 antibody; Siah-1 antibody; Siah-1a antibody; SIAH2 antibody; E3 ubiquitin-protein ligase SIAH2 antibody; Seven in absentia homolog 2 antibody; Siah-2 antibody; hSiah2 antibody;
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应用
WB: 1:500-1:2000
IHC-P: 1:100-1:300
IF: 1:100-1:500
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Fig1: Western Blot analysis of various cells using Siah-1/2 Polyclonal Antibody diluted at 1:500
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