Anti-V-ATPase H antibody
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概述
- 产品描述This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular organelles. V-ATPase-dependent organelle acidification is necessary for multiple processes including protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. The encoded protein is the regulatory H subunit of the V1 domain of V-ATPase, which is required for catalysis of ATP but not the assembly of V-ATPase. Decreased expression of this gene may play a role in the development of type 2 diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
- 产品名称Anti-V-ATPase H antibody
- 分子量55 kDa
- 种属反应性Human, Mouse
- 验证应用WB, IHC-P
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human ATP6V1H. AA range:341-390
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称
- ATP6V1H antibody; CGI-11 antibody; V-type proton ATPase subunit H antibody; V-ATPase subunit H antibody; Nef-binding protein 1 antibody; NBP1 antibody; Protein VMA13 homolog antibody; V-ATPase 50/57 kDa subunits antibody; Vacuolar proton pump subunit H antibody; Vacuolar proton pump subunit SFD antibody;
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应用
WB: 1:500-1:2000
IHC-P: 1:100-1:300
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Fig1: Western Blot analysis of various cells using V-ATPase H Polyclonal Antibody. Secondary antibody（catalog#：HA1001) was diluted at 1:20000
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