Anti-P53 antibody
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概述
- 产品描述The p53 tumor suppressor protein plays a major role in cellular response to DNA damage and other genomic aberrations. Activation of p53 can lead to either cell cycle arrest and DNA repair or apoptosis. It is involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. p53 is phosphorylated at multiple sites in vivo and by several different protein kinases in vitro. P53 is found in increased amounts in a wide variety of transformed cells. P53 is frequently mutated or inactivated in about 60% of cancers.
- 产品名称Anti-P53 antibody
- 分子量~53kDa
- 种属反应性Human
- 验证应用WB,ICC
- 抗体类型兔多抗
- 免疫原peptide
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified
- 亚细胞定位Cytoplasm, Nucleus
- 其它名称
- Antigen NY-CO-13 antibody
- BCC7 antibody
- Cellular tumor antigen p53 antibody
more
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应用
WB: 1:1,000
ICC: 1:100
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Fig1: Western blot analysis on 293 cell lysates using anti-p53 rabbit polyclonal antibodies.
Fig2: Immunofluorescent staining of A431 cells using anti- p53 rabbit polyclonal antibody.
特别提示:本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!