Anti-3β-HSD7 antibody
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概述
- 产品描述This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene.
- 产品名称Anti-3β-HSD7 antibody
- 分子量41 kDa
- 种属反应性Human, Mouse, Rat
- 验证应用WB
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human HSD3B7. AA range:121-170
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称HSD3B7 antibody; 3 beta-hydroxysteroid dehydrogenase type 7 antibody; 3 beta-hydroxysteroid dehydrogenase type VII antibody; 3-beta-HSD VII antibody; 3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase antibody; C(27) 3-beta-HSD antibody; Cholest-5-ene-3-beta antibody; 7-alpha-diol 3-beta-dehydrogenase antibody;
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Fig1: Western Blot analysis of various cells using 3β-HSD7 Polyclonal Antibody diluted at 1:1000
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