Anti-VEGFR1 antibody

Anti-VEGFR1 antibody

• 概述

• 产品描述Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. Vascular endothelial growth factor receptor 1 is a protein that in humans is encoded by the FLT1 gene. Oncogene FLT belongs to the src gene family and is related to oncogene ROS. Like other members of this family, it shows tyrosine protein kinase activity that is important for the control of cell proliferation and differentiation. The sequence structure of the FLT gene resembles that of the FMS gene; hence, Yoshida et al. (1987) proposed the name FLT as an acronym for FMS-like tyrosine kinase. FLT1 has been shown to interact with PLCG1 and vascular endothelial growth factor B (VEGF-B).

• 产品名称Anti-VEGFR1 antibody

• 分子量150 kDa

• 种属反应性Human,Mouse,Rat

• 验证应用WB,IHC-P

• 抗体类型兔多抗

• 免疫原peptide

• 偶联Non-conjugated

• 性能

• 形态Liquid

• 浓度1 mg/mL.

• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.

• 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

• 亚型IgG

• 纯化方式Peptide affinity purified

• 亚细胞定位Cell membrane, endosome.

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• 其它名称EC 2.7.10.1 antibody
  FLT 1 antibody
  FLT antibody
  Flt-1 antibody
  FLT1 antibody
  Fms like tyrosine kinase 1 antibody
  Fms related tyrosine kinase 1 antibody
  Fms related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) antibody
  Fms related tyrosine kinase 1 vascular endothelial growth factor/vascular permeability factor receptor antibody
  Fms-like tyrosine kinase 1 antibody
  FRT antibody
  Soluble VEGF receptor 1 14 antibody
  Soluble VEGFR1 variant 2 antibody
  Soluble VEGFR1 variant 21 antibody
  Tyrosine protein kinase FRT antibody
  Tyrosine protein kinase receptor FLT antibody
  Tyrosine-protein kinase FRT antibody
  Tyrosine-protein kinase receptor FLT antibody
  Vascular endothelial growth factor receptor 1 antibody
  Vascular endothelial growth factor vascular permeability factor receptor antibody
  Vascular permeability factor receptor 1 antibody
  Vascular permeability factor receptor antibody
  VEGFR 1 antibody
  VEGFR-1 antibody
  VEGFR1 antibody
  VGFR1_HUMAN antibody

  more

• 应用

  WB: 1:1,000
  IHC-P: 1:200

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  Fig1: Western blot analysis of VEGFR1 on mouse liver tissue lysate using anti- VEGFR1 antibody at 1/1000 dilution.

   

  

  Fig2: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-VEGFR1 antibody. Counter stained with hematoxylin.

   

  

  Fig3: Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-VEGFR1 antibody. Counter stained with hematoxylin.

   

  

  Fig4: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-VEGFR1 antibody. Counter stained with hematoxylin.

   

  

  Fig5: Immunohistochemical analysis of paraffin-embedded mouse heart tissue using anti-VEGFR1 antibody. Counter stained with hematoxylin.

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