Anti-PDZK1 antibody
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概述
- 产品描述A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. May function to connect SCARB1 with the cellular machineries for intracellular cholesterol transport and/or metabolism. May be involved in the regulation of proximal tubular Na(+)-dependent inorganic phosphate cotransport therefore playing an important role in tubule function (By similarity).
- 产品名称Anti-PDZK1 antibody
- 分子量57 KDa
- 种属反应性Human,Mouse,Rat,Rabbit
- 验证应用WB
- 抗体类型兔多抗
- 免疫原KLH conjugated synthetic peptide derived from human PDZK1 1-100/519
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
- 存储缓冲液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 亚型IgG
- 纯化方式affinity purified by Protein A
- 亚细胞定位Cytoplasm. Membrane. Associated with peripheral membranes. Localizes to the apical compartment of proximal tubular cells and to sinusoidal liver membranes.
- 其它名称CAP70
CFTR associated protein of 70 kDa
CFTR associated protein, 70-KD
CFTR-associated protein of 70 kDa
CLAMP
D3Ertd537e
Dietary Pi-regulated RNA-1
Diphor-1
mPDZK1
Na(+)/H(+) exchange regulatory cofactor NHE-RF3
Na(+)/H(+) exchanger regulatory factor 3
Na/Pi cotransporter C-terminal-associated protein 1
Na/Pi cotransporter C-terminal-associated protein
NaPi Cap1
NaPi-Cap1
NaPiCap1
NHERF 3
NHERF-3
NHERF3
NHRF3_HUMAN
OTTHUMP00000015572
PDZ domain containing 1
PDZ domain containing protein 1
PDZ domain-containing protein 1
PDZD1
PDZK1
Sodium hydrogen exchanger regulatory factor 3
Sodium-hydrogen exchanger regulatory factor 3
1700023D20Rik
2610507N21Rik
4921513F16Rik
AI267131
AI314638
AL022680
C terminal linking and modulating protein.
more
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Fig1: Sample:
Liver (Mouse) Lysate at 40 ug
Primary: Anti- PDZK1at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 57 kD
Observed band size: 57 kD
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
