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别名: | IP3 Receptor | ||
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适用物种: | Human,Mouse,Rat | ||
验证应用: | IHC-P,FC,WB | ||
种属: | 兔多抗 | ||
储存条件: | -20℃ |
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货号 | 规格 | 可用库存 | 销售价(RMB) | 您的折扣价(RMB) | 购买数量 |
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熔点: | |
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密度: | |
储存条件: | -20℃ |
Anti-IP3 Receptor antibody
产品描述Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways.
产品名称Anti-IP3 Receptor antibody
分子量314 kDa
种属反应性Human,Mouse,Rat
验证应用IHC-P,FC,WB
抗体类型兔多抗
免疫原Synthetic peptide within C-terminal human IP3 Receptor.
偶联Non-conjugated
形态Liquid
浓度1 mg/mL.
存放说明Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
存储缓冲液1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
亚型IgG
纯化方式Peptide affinity purified.
亚细胞定位Cytoplasm. Cytoplasmic vesicle. Endoplasmic reticulum. Membrane.
其它名称
WB: 1:500-1:1,000
IHC-P: 1:50-1:200
FC: 1:50-1:100
Fig1: Western blot analysis of IP3 Receptor on Hela cell lysate using anti-IP3 Receptor antibody at 1/500 dilution.
Fig2: Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-IP3 Receptor antibody. Counter stained with hematoxylin.
Fig3: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-IP3 Receptor antibody. Counter stained with hematoxylin.
Fig4: Flow cytometric analysis of SH-SY-5Y cells with IP3 Receptor antibody at 1/100 dilution (fuchsia) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.
特别提示:本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!