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Anti-IP3 Receptor antibody

Anti-IP3 Receptor antibody
别名: IP3 Receptor
适用物种: Human,Mouse,Rat  
验证应用: IHC-P,FC,WB  
种属: 兔多抗  
储存条件: -20℃ 
Anti-IP3 Receptor antibody
货号 规格 可用库存 销售价(RMB) 您的折扣价(RMB) 购买数量
ZY6803-17R-50 μl 兔多抗 现货 1500.00 1500
ZY6803-17R-100 μl 兔多抗 现货 2500.00 2500
熔点:
密度:
储存条件: -20℃

 

Anti-IP3 Receptor antibody

 

  • 概述

  • 产品描述Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways.

  • 产品名称Anti-IP3 Receptor antibody

  • 分子量314 kDa

  • 种属反应性Human,Mouse,Rat

  • 验证应用IHC-P,FC,WB

  • 抗体类型兔多抗

  • 免疫原Synthetic peptide within C-terminal human IP3 Receptor.

  • 偶联Non-conjugated

  • 性能

  • 形态Liquid

  • 浓度1 mg/mL.

  • 存放说明Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.

  • 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

  • 亚型IgG

  • 纯化方式Peptide affinity purified.

  • 亚细胞定位Cytoplasm. Cytoplasmic vesicle. Endoplasmic reticulum. Membrane.

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  • 其它名称4 antibody
    5-trisphosphate receptor antibody
    5-trisphosphate receptor type 1 antibody
    DKFZp313E1334 antibody
    DKFZp313N1434 antibody
    inositol 1 4 5 triphosphate receptor type 1 antibody
    Inositol 1 4 5 trisphosphate Receptor Type 1 antibody
    Inositol 1 antibody
    InsP3R1 antibody
    IP3 antibody
    IP3 receptor antibody
    IP3 receptor isoform 1 antibody
    IP3R 1 antibody
    IP3R antibody
    IP3R1 antibody
    ITPR 1 antibody
    Itpr1 antibody
    ITPR1_HUMAN antibody
    SCA15 antibody
    SCA16 antibody
    SCA29 antibody
    Type 1 inositol 1 4 5 trisphosphate receptor antibody
    Type 1 inositol 1 antibody
    Type 1 InsP3 receptor antibody

    more
  • 应用

    WB: 1:500-1:1,000
    IHC-P: 1:50-1:200
    FC: 1:50-1:100

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    Fig1: Western blot analysis of IP3 Receptor on Hela cell lysate using anti-IP3 Receptor antibody at 1/500 dilution.

     

    Fig2: Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-IP3 Receptor antibody. Counter stained with hematoxylin.

     

    Fig3: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-IP3 Receptor antibody. Counter stained with hematoxylin.

     

    Fig4: Flow cytometric analysis of SH-SY-5Y cells with IP3 Receptor antibody at 1/100 dilution (fuchsia) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.

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