Anti-GPR120 antibody
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概述
- 产品描述Receptor for medium and long-chain free fatty acid (FAA). Signals via a G(q)/G(11)-coupled pathway. Acts as a receptor for omega-3 fatty acids and mediates robust anti-inflammatory effects particulary in macrophages and fat cells. The anti-inflammatory effects involve inhibition of TAK1 through a beta-arrestin 2 (ARRB2)/TAB1 dependent effect but independent of G(q)/G(11)-coupled pathway. Mediates potent insulin sensitizing and antidiabetic effects by repressing macrophage-induced tissue inflammation. May mediates the taste of fatty acids.
- 产品名称Anti-GPR120 antibody
- 分子量42 KDa
- 种属反应性Human,Mouse,Rat,Dog,Pig,Cow,Rabbit
- 验证应用WB
- 抗体类型兔多抗
- 免疫原KLH conjugated synthetic peptide derived from human G protein coupled receptor 120 21-120/377
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
- 存储缓冲液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 亚型IgG
- 纯化方式affinity purified by Protein A
- 亚细胞定位Cell membrane. Colocalized with ARRB2 following DHA treatment.
- 其它名称G protein coupled receptor 120
GPCR GPR120
G protein coupled receptor 129
G protein coupled receptor GT01
G protein coupled receptor PGR 4
G protein coupled receptor PGR4
G-protein coupled receptor 120
G-protein coupled receptor 129
G-protein coupled receptor GT01
G-protein coupled receptor PGR4
GPR 120
GPR 129
GPR120
GPR129
GT01
HGNC:19345
MGC119984
O3FA1_HUMAN
O3FAR1
Omega-3 fatty acid receptor 1
PGR 4
PGR4
GPCR120.
more
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Fig1: Sample:
Lung (Mouse) Lysate at 40 ug
Primary: Anti-GPR120 at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 42 kD
Observed band size: 42 kD
特别提示:本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!