Anti-EIF4B antibody [D7-F5]

Anti-EIF4B antibody [D7-F5]

• 概述

• 产品描述The initiation of protein synthesis in eukaryotic cells is regulated by interactions between protein initiation factors and RNA molecules. These interactions are facilitated, in part, by the eukaryotic initiation factor 4 family (eIF4) of proteins that are involved in the early initiation of protein synthesis. eIF4B (eukaryotic translation initiation factor 4B) is a 611 amino acid protein that contains one RNA recognition motif and belongs to the eIF4 protein family. Required for proper mRNA/ribosome binding, eIF4B associates with other eIF4 proteins, such as eIF4A, and promotes the ATP-dependent unwinding activity of select eukaryotic initiation factors. The gene encoding eIF4B maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome.
• 产品名称Anti-EIF4B antibody [D7-F5]
• 分子量80 kDa
• 种属反应性Human,Mouse
• 验证应用WB,ICC,IHC-P,FC
• 抗体类型小鼠单抗
• 免疫原Recombinant protein
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
• 亚型IgG2b
• 纯化方式Protein A purified.
• 亚细胞定位Cytosol.
• 其它名称
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• 应用

  WB: 1:500-1:2,000
  ICC: 1:100-1:500
  IHC-P: 1:100-1:500
  FC: 1:100-1:200

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  Fig1: Western blot analysis of EIF4B on human EIF4B recombinant protein using anti-EIF4B antibody at 1/1,000 dilution.

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