Anti-Estrogen Related Receptor alpha antibody
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概述
- 产品描述Estrogen related receptor alpha (ERRα) is a nuclear receptor in the superfamily of ligand-regulated transcription factors and is a member of the NR3B orphan nuclear receptor subgroup (consisting of α, β and γ). ERRα plays a role in modulating the estrogen signaling pathway. In addition, the expression of ERRα has been shown to increase during fasting and cold exposure. ERRα may be important for regulating mitochondrial biogenesis and oxidative metabolism by acting directly on genes necessary for mitochondrial function. Mice lacking ERRα are unable to maintain their body temperature in the cold. ERRα may also be involved in the maintenance and formation of cartilage. This information could be useful in finding therapeutic agents for a variety of diseases affecting the joints.
- 产品名称Anti-Estrogen Related Receptor alpha antibody
- 分子量53 kDa
- 种属反应性Human
- 验证应用WB,FC
- 抗体类型兔多抗
- 免疫原Recombinant protein
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Protein affinity purified.
- 亚细胞定位Nucleus.
- 其它名称Err 1 antibody
ERR a antibody
ERR alpha antibody
ERR-alpha antibody
Err1 antibody
ERR1 protein antibody
ERR1_HUMAN antibody
ERRa antibody
ERRalpha antibody
ESRL 1 antibody
ESRL1 antibody
ESRR A antibody
Esrra antibody
Estrogen receptor like 1 antibody
Estrogen receptor related 1 antibody
estrogen receptor related receptor alpha antibody
Estrogen receptor-like 1 antibody
Estrogen related receptor alpha antibody
Estrogen-related receptor alpha antibody
Estrra antibody
hERR1 antibody
NR3B1 antibody
Nuclear receptor subfamily 3 group B member 1 antibody
Steroid hormone receptor ERR1 antibody
more
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应用
WB: 1:500
FC: 1:50-1:100
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Fig1: Western blot analysis of Estrogen Related Receptor alpha on MCF-7 cell lysate using anti-Estrogen Related Receptor alpha antibody at 1/200 dilution.
Fig2: Flow cytometric analysis of MCF-7 cells with Estrogen Related Receptor alpha antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
