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ClinMax™ Human Interferon Gamma (IFN-γ) Quantitative ELISA Kit
ClinMax™ Human Interferon Gamma(IFN-γ)Quantitative ELISA Kit is specifically designed for the accurate quantitation of human Interferon-γ (IFN-γ) from cell culture supernatant, serum and plasma. Interferon-γ is produced mainly by activated T cells and NK cells. It is a proinflammatory cytokine that activates macrophages and endothelial cells, but it also regulates immune responses by effecting APC and T and B cells. Production of IFN-γ by helper T cells as well as cytotoxic T cells is a hallmark of the TH1-type phenotype, thus, high-level production of IFN-γ is typically associated with effective host defense against intracellular pathogens. IFN-γ is capable of orchestrating numerous protective functions to heighten immune responses in infections and cancers. It can exhibit its immunomodulatory effects by enhancing antigen processing and presentation, increasing leukocyte trafficking, inducing an anti-viral state, boosting the anti-microbial functions and affecting cellular proliferation and apoptosis.
This immunoassay is designed to quantitate human IFN-γ that is present in human serum, plasma, buffered solution, or cell culture. It has been calibrated against a highly purified human IFN-γ and is evaluated with unclassified standard from NIBSC/WHO.
It is for research use only.
The unopened kit is stable for 12 months from the date of manufacture if stored at 2°C to 8°C. The opened kit should be stored per components table. The shelf life is 30 days from the date of opening.