Anti-UFO antibody [C4-A8]

Anti-UFO antibody [C4-A8]

• 概述

• 产品描述Tyrosine-protein kinase receptor UFO is an enzyme that in humans is encoded by the AXL gene. The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, the Axl protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation. This receptor can also mediate cell aggregation by homophilic binding. Axl is a chronic myelogenous leukemia-associated oncogene and also associated with colon cancer and melanoma. AXL receptor tyrosine kinase has been shown to interact with TENC1.Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival.
• 产品名称Anti-UFO antibody [C4-A8]
• 分子量98 kDa
• 种属反应性Human
• 验证应用WB,ICC
• 抗体类型小鼠单抗
• 免疫原Recombinant protein within human UFO 1-150 aa.
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• 亚型IgG1
• 纯化方式Protein G purified.
• 亚细胞定位Cell membrane
• 其它名称
• • Adhesion related kinase antibody
  • AI323647 antibody
  • Ark antibody
  more

• 应用

  WB: 1:500
  ICC: 1:200-1:500

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  Fig1: Western blot analysis of UFO on recombinant protein lysate using anti-UFO antibody at 1/20,000 dilution.

   

  

  Fig2: ICC staining UFO (green) in SW480 cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！