Anti-MASP2 antibody [F3-4]
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概述
- 产品描述Mannan-binding lectin serine protease 2 also known as mannose-binding protein-associated serine protease 2 (MASP-2) is an enzyme that in humans is encoded by the MASP2 gene. MASP-2 involved in the complement system. MASP-2 is very similar to the C1s molecule, of the classical complement pathway, and they are thought to have a common evolutionary ancestor. When the carbohydrate-recognising heads of MBL bind to specifically arranged mannose residues on the surface of a pathogen, MASP-2 is activated to cleave complement components C4 and C2 into C4a, C4b, C2a, and C2b.
- 产品名称Anti-MASP2 antibody [F3-4]
- 分子量~76kDa
- 种属反应性Human
- 验证应用WB
- 抗体类型小鼠单抗
- 免疫原peptide
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度2 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG2b
- 纯化方式Protein A purified.
- 亚细胞定位Secreted
- 其它名称
- Mannan binding lectin serine peptidase 2 antibody
- Mannan binding lectin serine protease 2 antibody
- Mannose binding protein associated serine protease 2 antibody
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Fig1: Western blot analysis on human serum lysates using anti-MASP2 mouse mAb.
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