![Anti-CSF1R antibody [B9-B9]](images/202012/goods_img/92807_G_1608034481944.jpg)
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| 货号 | 规格 | 可用库存 | 销售价(RMB) | 您的折扣价(RMB) | 购买数量 | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| ZY6708-56M-50 μl | 小鼠单抗 | 现货 | 1500 | ||||||||
| ZY6708-56M-100 μl | 小鼠单抗 | 现货 | 2500 | ||||||||
| 熔点: | |
|---|---|
| 密度: | |
| 储存条件: | -20℃ |
Anti-CSF1R antibody [B9-B9]
产品描述c-Fms/CSF-1R, also designated macrophage colony-stimulating factor receptor (M-CSFR), FIM2 or CD115, is a transmembrane tyrosine kinase receptor belonging to the CSF1/PDGF receptor family. It is encoded by the c-Fms proto-oncogene and is expressed in mononuclear phagocytes, oocytes, decidual cells, trophoblastic cells and some myoblasts. It is important for growth and differentiation of myeloid cells and its function can be regulated by SLAP-2. c-Fms/CSF-1R is responsible for mediating all of the functions of M-CSF. M-CSF is a glycoprotein required for the proliferation and differentiation of mononuclear phagocytes, including osteoclasts. M-CSF has also been identified as an important mediator of the inflammatory response and can regulate the release of proinflammatory cytokines from macrophages.
产品名称Anti-CSF1R antibody [B9-B9]
分子量108 kDa
种属反应性Human
验证应用WB,ICC,IHC-P
抗体类型小鼠单抗
免疫原Recombinant protein
偶联Non-conjugated
形态Liquid
浓度2 mg/mL.
存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
存储缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
亚型IgG2b
纯化方式Protein A purified.
亚细胞定位Membrane.
其它名称
C FMS antibody
CD 115 antibody
CD115 antibody
WB: 1:500-1:2,000
ICC: 1:100-1:200
IHC-P: 1:100-1:200
Fig1: Western blot analysis of CSF1R on human CSF1R recombinant protein using anti-CSF1R antibody at 1/1,000 dilution.
Fig2: Western blot analysis of CSF1R on HEK293 (1) and CSF1R-hIgGFc transfected HEK293 (2) cell lysate using anti-CSF1R antibody at 1/1,000 dilution.
Fig3: ICC staining CSF1R (green) in HepG2 cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig4: Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-CSF1R antibody. Counter stained with hematoxylin.
Fig5: Immunohistochemical analysis of paraffin-embedded human esophageal tissue using anti-CSF1R antibody. Counter stained with hematoxylin.
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