Anti-Cacng4 antibody

Anti-Cacng4  antibody

• 概述

• 产品描述Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization.

• 产品名称Anti-Cacng4 antibody

• 分子量37 kDa

• 种属反应性Human,Rat

• 验证应用WB,ICC,IHC-P,FC

• 抗体类型兔多抗

• 免疫原Synthetic peptide within rat Cacng4 aa 150-250.

• 偶联Non-conjugated

• 性能

• 形态Liquid

• 浓度1 mg/mL.

• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.

• 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

• 亚型IgG

• 纯化方式Peptide affinity purified.

• 亚细胞定位Cell membrane.

• 其它名称CACNG4 antibody
  Calcium channel voltage dependent gamma subunit 4 antibody
  CCG4_HUMAN antibody
  Neuronal voltage gated calcium channel gamma 4 subunit antibody
  Neuronal voltage-gated calcium channel gamma-4 subunit antibody
  TARP gamma-4 antibody
  Transmembrane AMPAR regulatory protein gamma-4 antibody
  Voltage dependent calcium channel gamma 4 subunit antibody
  Voltage-dependent calcium channel gamma-4 subunit antibody

  more

• 应用

  WB: 1:500-1:1,000
  ICC: 1:50-1:100
  IHC-P: 1:50
  FC: 1:50-1:100

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  Fig1: Western blot analysis of Cacng4 on MCF-7 cell lysate using anti-Cacng4 antibody at 1/500 dilution.

   

  

  Fig2: ICC staining Cacng4 in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

   

  

  Fig3: ICC staining Cacng4 in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

   

  

  Fig4: Immunohistochemical analysis of paraffin-embedded rat testis tissue using anti- Cacng4 antibody. Counter stained with hematoxylin.

   

  

  Fig5: Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti- Cacng4 antibody. Counter stained with hematoxylin.

   

  

  Fig6: Flow cytometric analysis of SH-SY5Y cells with Cacng4 antibody at 1/100 dilution (fuchsia) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.

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