Anti-KLHL12 antibody [B1-G2]
-
概述
- 产品描述KLHL12 (kelch-like protein 12), also known as C3IP1 (CUL3-interacting protein 1), DKIR or FLJ27152, is a 568 amino acid protein that is a component of an ubiquitin-protein E3 ligase complex, which includes at least CUL-3. KLHL12 is a substrate-specific adapter for the complex, which negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of Dvl-3. KLHL12 contains six Kelch repeats and one BTB (POZ) domain, which is required for interaction with CUL-3. KLHL12 has highest expression in testis, with lower levels found in the submandibular salivary gland. The gene that encodes KLHL12 maps to human chromosome 1q32.1.
- 产品名称Anti-KLHL12 antibody [B1-G2]
- 分子量63 kDa
- 种属反应性Human
- 验证应用WB
- 抗体类型小鼠单抗
- 免疫原Recombinant protein
- 偶联Non-conjugated
-
性能
- 形态Liquid
- 浓度2 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
- 亚型IgG1
- 纯化方式Protein A purified.
- 亚细胞定位Cytoplasmic vesicle.
- 其它名称
- C3IP1 antibody
- CUL3 interacting protein 1 antibody
- CUL3-interacting protein 1 antibody
more
-
-
Fig1: Western blot analysis of KLHL12 on Hela cell lysate using anti-KLHL12 antibody at 1/1,000 dilution.
特别提示:本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!