Anti-POU3F2 antibody [B8-H12]

Anti-POU3F2 antibody [B8-H12]

• 概述

• 产品描述The Brn family of transcription factors are found in a highly restricted subset of neurons and are critical to the early embryonic development of the central nervous system. Brn-1 and Brn-2 are class III POU domain proteins. Expressed during the development of the forebrain and coexpressed in most layer II-V cortical neurons, Brn-1 and Brn-2 appear to critically control the initiation of radial migration of cortical neurons. Brn-2 is thought to be involved in smooth muscle cell development and differentiation. Brn-3 is a class IV POU domain protein. Three Brn-3 proteins have been described and are designated Brn-3a, Brn-3b and Brn-3c. Brn-3a has two functional transactivating domains, one at the amino terminus and one at the carboxy terminus. While Brn-3a and Brn-3c stimulate transcription, Brn-3b generally functions as a transcriptional repressor. However, Brn-3b, but not Brn-3a, has been shown to regulate the expression of the acetylcholine receptor.
• 产品名称Anti-POU3F2 antibody [B8-H12]
• 分子量47 kDa
• 种属反应性Human
• 验证应用WB
• 抗体类型小鼠单抗
• 免疫原Recombinant protein
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
• 亚型IgG1
• 纯化方式Protein A purified.
• 亚细胞定位Nucleus.
• 其它名称
  • Brain 2 antibody
  • Brain specific homeobox/POU domain protein 2 antibody
  • Brain-2 antibodyBrain-specific homeobox/POU domain protein 2 antibody
  more

• 应用

  WB: 1:500-1:2,000

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  Fig1: Western blot analysis of POU3F2 on human POU3F2 recombinant protein using anti-POU3F2 antibody at 1/1,000 dilution.

   

  

  Fig2: Western blot analysis of POU3F2 on HeLa (1) and SK-N-SH (2) cell lysate using anti-POU3F2 antibody at 1/1,000 dilution.

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