Anti-CDH17 antibody [D10-E1]

Anti-CDH17 antibody [D10-E1]

• 概述

• 产品描述This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants.
• 产品名称Anti-CDH17 antibody [D10-E1]
• 分子量92 kDa
• 种属反应性Human
• 验证应用WB,IHC-P
• 抗体类型小鼠单抗
• 免疫原Recombinant protein
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
• 亚型IgG1
• 纯化方式Protein A purified.
• 亚细胞定位Cell membrane
• 其它名称
  • BILL-cadherin antibody
  • CAD17_HUMAN antibody
  • Cadherin 16 antibody
  more

• 应用

  WB: 1:500-1:2,000
  IHC-P: 1:50-1:200

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  Fig1: Western blot analysis of CDH17 on human CDH17 recombinant protein using anti-CDH17 antibody at 1/1,000 dilution.

   

  

  Fig2: Western blot analysis of CDH17 on HEK293 (1) and CDH17-hIgGFc transfected HEK293 (2) cell lysate using anti-CDH17 antibody at 1/1,000 dilution.

   

  

  Fig3: Immunohistochemical analysis of paraffin-embedded human rectum cancer tissues using anti-CDH17 antibody. Counter stained with hematoxylin.

   

  

  Fig4: Immunohistochemical analysis of paraffin-embedded human colon tissues using anti-CDH17 antibody. Counter stained with hematoxylin.

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