Anti-GPX1 antibody [A6-C0-B9]

Anti-GPX1 antibody [A6-C0-B9]

• 概述

• 产品描述The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage. Other studies indicate that H2O2 is also essential for growth-factor mediated signal transduction, mitochondrial function, and maintenance of thiol redox-balance; therefore, by limiting H2O2 accumulation, glutathione peroxidases are also involved in modulating these processes. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme is the most abundant, is ubiquitously expressed and localized in the cytoplasm, and whose preferred substrate is hydrogen peroxide.
• 产品名称Anti-GPX1 antibody [A6-C0-B9]
• 分子量22 kDa
• 种属反应性Human
• 验证应用WB,IHC-P,FC
• 抗体类型小鼠单抗
• 免疫原Recombinant protein within human Glutathione Peroxidase 1 aa 20-250.
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
• 亚型IgG2b
• 纯化方式ProG purified.
• 亚细胞定位Cytosol. Mitochondrion.
• 其它名称
  • AL033363 antibody
  • Cellular glutathione peroxidase antibody
  • Glutathione peroxidase 1 antibody
  more

• 应用

  WB: 1:500-1:1,000
  IHC-P: 1:50-1:200
  FC: 1:50-1:100

•  

  

  Fig1: Western blot analysis of Glutathione Peroxidase 1 on THP-1 cell lysate using anti- Glutathione Peroxidase 1 antibody at 1/500 dilution.

   

  

  Fig2: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti- Glutathione Peroxidase 1 antibody. Counter stained with hematoxylin.

   

  

  Fig3: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti- Glutathione Peroxidase 1 antibody. Counter stained with hematoxylin.

   

  

  Fig4: Flow cytometric analysis of HepG2 cells with Glutathione Peroxidase 1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-mouse IgG was used as the secondary antibody.

特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！